Best Mussels in Uptown, Chicago
The 5 top-rated mussels in Uptown, Chicago, ranked by flavor score.
The top choice is mussels at Hopleaf (5148 N Clark St), with a flavor score of 89 out of 100 from 189 diner ratings. Flavor scores come from what real diners say in their reviews. Last updated August 27, 2026. How flavor scores work →
Best Mussels across Chicago→- Ranked #1At Hopleaf5148 N Clark St
Mussels are praised for their freshness and rich, flavorful broth, served with perfectly cooked fries and garlic aioli.
- Ranked #2At Tala House5022 N Clark St
- Ranked #3At Hopleaf5148 N Clark St
- Ranked #4At Bar Roma5101 N Clark St Ste 1
- Ranked #5At Spacca Napoli Pizzeria1769 W Sunnyside Ave
Which one is the GOAT?
You can crown one per category, so choose wisely.